Page 17 - Dandaloo Sale Catalogue eBook.pdf

Arthrogryposis Multiplex (AM) - Neuropathic Hydrocephalus (NH)
Contractural Arachnodactyly (CA) - Developmental Duplication (DD)

AM, NH, CA and DD are simple recessive gene defects, caused Geneprob will identify ‘at risk’ animals in the breed database and
by the presence of a single pair of inherited genes. The red gene assign them a status for AMS, NHS, CAS and DDS as follows;
in Angus cattle is a common example of recessive inheritance – AMFU, NHFU, CAFU and/or DDFU= free by pedigree
the gene must be present on both sides of the pedigree for full inference, untested
expression. AMS %, NHS%, CAS% and/or DDS% = a suspected carrier
(% = level of suspicion) but un-tested.Requires testing to validate
If a carrier sire and a carrier dam are mated, 25% of the progeny true status.
will be clear of the defect, 50% will be carriers, and 25% will be AMF, NHF, CAF and/or DDF = tested free of the defect.
affected. AMC, NHC, CAC and/or DDC = tested carrier of the defect.
A DNA test has been developed to identify carrier animals so These GeneProb analysis tests are performed every seven days.
these defects can be eliminated from the breed. Genotyping for these mutations should, with 100% accuracy,
After such DNA testing, you will be given one of two results; expedite elimination of these genes from the Angus population.
AMF, NHF, CAF or DDF = tested free of the gene
AMC, NHC, CAC or DDC = tested carriers of the defect. If you are unsure of any aspect of these genetic defects please
don’t hesitate to ring us directly or contact the Angus NZ on (06)
But, to assist with the identification of carrier animals (prior 323 4484.
to DNA testing) a ‘probability test’ has been developed - using
updated test results and animals’ pedigrees, known as Geneprob.
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