Page 48 - Tapiri Angus 2021 Catalogue ebook
P. 48

Arthrogryposis Multiplex (AM) - Neuropathic Hydrocephalus (NH)
                  Contractural Arachnodactyly (CA) - Developmental Duplication (DD)
       AM, NH, CA and DD are simple recessive gene defects, caused   Geneprob will identify ‘at risk’ animals in the breed database and
       by the presence of a single pair of inherited genes. The red gene   assign them a status for AMS, NHS, CAS and DDS as follows;
       in Angus cattle is a common example of recessive inheritance –
       the gene must be present on both sides of the pedigree for full   AMFU, NHFU, CAFU and/or DDFU= free by pedigree
       expression.                                            inference, untested
                                                              AMS %, NHS%, CAS% and/or DDS% = a suspected carrier
       If a carrier sire and a carrier dam are mated, 25% of the progeny   (% = level of suspicion) but un-tested.Requires testing to validate
       will be clear of the defect, 50% will be carriers, and 25% will be   true status.
       affected.                                              AMF, NHF, CAF and/or DDF = tested free of the defect.
       A DNA test has been developed to identify carrier animals so    AMC, NHC, CAC and/or DDC = tested carrier of the defect.
       these defects can be eliminated from the breed.        These GeneProb analysis tests are performed every seven days.
       After such DNA testing, you will be given one of two results;  Genotyping for these mutations should, with 100% accuracy,
                                                              expedite elimination of these genes from the Angus population.
       AMF, NHF, CAF or DDF = tested free of the gene
       AMC, NHC, CAC or DDC = tested carriers of the defect.  If you are unsure of any aspect of these genetic defects please
                                                              don’t hesitate to ring us directly or contact the Angus NZ
       But, to assist with the identification of carrier animals (prior   on (06) 323 4484.
       to DNA testing) a ‘probability test’ has been developed - using
       updated test results and animals’ pedigrees, known as Geneprob.
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