Page 18 - Waigroup Pinebank Pinehill Angus 2021 Catalogue ebook

Genetic Defects -

Arthrogryposis Multiplex (AM), Neuropathic Hydrocephalus
(NH), Contractural Arachnodactyly (CA), Developmental
Duplication (DD) AM, NH, CA and DD are simple recessive
gene defects, caused by the presence of a single pair of
inherited genes. The red gene in Angus cattle is a common
example of recessive inheritance – the gene must be present
on both sides of the pedigree for full expression.
If a carrier sire and a carrier dam are mated, 25% of the
progeny will be clear of the defect, 50% will be carriers, and
25% will be affected.

A DNA test has been developed to identify carrier animals so
these defects can be eliminated from the breed.
After such DNA testing, you will be given one of two results;

AMF, NHF, CAF or DDF = tested free of the gene
AMC, NHC, CAC or DDC = tested carriers of the defect.
But, to assist with the identification of carrier animals (prior
to DNA testing) a ‘probability test’ has been developed -
using updated test results and animals’ pedigrees, known
as Geneprob. Geneprob will identify ‘at risk’ animals in the
breed database and assign them a status for AMS, NHS,
CAS and DDS as follows;
AMFU, NHFU, CAFU and/or DDFU
= free by pedigree inference, untested
MS %, NHS%, CAS% and/or DDS% = a suspected carrier
(% = level of suspicion) but un-tested.
Requires testing to validate true status.
AMF, NHF, CAF and/or DDF = tested free of the defect.
AMC, NHC, CAC and/or DDC = tested carrier of the
defect. These GeneProb analysis tests are performed
every seven days.
Genotyping for these mutations should, with 100% accuracy,
expedite elimination of these genes from the Angus
population.
If you are unsure of any aspect of these genetic defects
please don’t hesitate to ring us directly or contact the
AngusNZ on 06 323 4484.
All bulls entered in this catalogue have a genetic status of
Free or Free untested for the genetic defects mentioned
above.
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